Frequently Asked Questions on Coffee and Biohacking

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Frequently Asked Questions on Coffee and Biohacking

 

1. What Is Biohacking and Where Does Coffee Fit In?

Definition:

  • Biohacking = DIY biology optimization
  • Aims to enhance physical, cognitive, and emotional performance

Coffee's Role:

  • Acts as a natural nootropic
  • Used for:
    • Boosting energy and focus
    • Enhancing alertness and performance
    • Supporting fasting and productivity routines

2. What Are the Main Bioactive Compounds in Coffee (Besides Caffeine)?

Key Compounds and Effects:

  • Trigonelline: Neuroprotective potential; degrades to niacin during roasting
  • Chlorogenic Acids (CGAs): Antioxidants that support glucose/lipid metabolism
  • Diterpenes (Cafestol, Kahweol): Anti-inflammatory/cancer properties, but may raise LDL
  • Melanoidins: Antioxidant properties that contribute to flavour and colour

Takeaway:

Coffee's health impact = synergistic effect of multiple compounds, not just Caffeine

3. How Do Biohackers Use Coffee for Cognitive Enhancement?

Popular Strategies:

  • Delay morning coffee to align with cortisol rhythm
  • Caffeine nap: Drink coffee, nap 20 minutes
  • Afternoon coffee dose for energy slumps
  • Track timing/dosage via apps or journals

Scientific Verdict:

  • Caffeine improves:
    • Alertness
    • Reaction time
    • Attention
  • Evidence is weak for advanced strategies (e.g. cortisol timing)
  • Perceived benefits often due to avoiding withdrawal or fatigue

4. How Is Coffee Used in Biohacking for Physical Performance?

Common Practices:

  • Pre-workout dose: 3–6 mg/kg caffeine, 30–60 min before exercise
  • Fasted training: Coffee to boost fat oxidation
  • Afternoon workouts + Caffeine = peak fat burning

Evidence Supports:

  • Improved endurance, reduced effort perception
  • Increased fat oxidation (acutely)
  • Less clear link to long-term fat loss

5. What Is Bulletproof Coffee (BPC), and Is It Effective?

Ingredients:

  • Black coffee + grass-fed butter + MCT oil

Claims:

  • Sustained energy (no crash)
  • Enhanced cognition via ketones
  • Suppressed hunger

Scientific Review:

  • MCTs do create ketones but effects on healthy brain performance are modest
  • No protein/fiber  poor full meal replacement
  • High saturated fat may raise LDL cholesterol

6. Are There Risks with Coffee Biohacking Practices?

Caffeine Overuse Risks:

  • Anxiety, jitteriness, insomnia
  • GI discomfort, increased BP/HR
  • Dependence and withdrawal

Bulletproof Coffee Risks:

  • Elevated LDL cholesterol
  • Nutrient deficiencies if used as a meal
  • High calorie content can lead to weight gain
  • Fat overload → digestive issues

7. Does Coffee's Full Chemistry Matter for Long-Term Health?

Yes Beyond Caffeine:

  • Chlorogenic acids: Anti-diabetic, anti-inflammatory, neuroprotective
  • Melanoidins and polyphenols Support immune and metabolic function

Associated Benefits:

  • Lower risk of:
    • Type 2 diabetes
    • Parkinson's disease
    • Liver disease

Summary:

Whole coffee = multifaceted health agent, not just a caffeine hit

8. Top Advice for Coffee Biohackers

Key Guidelines:

  • Moderation is key (≤400 mg/day for most)
  • Track your tolerance and response
  • Avoid unproven claims or extreme protocols
  • Don't substitute coffee for balanced meals
  • Consult a healthcare provider if you have medical concerns

Golden Rule:

 Let science not trends guide your use of coffee in biohacking.

 

Would you like to learn more about coffee? 👇 Check our more recent video 

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